Research Scientist, Solid-State NMR Analytical Centre,
Conjoint Lecturer School of Chemistry

Email: r.linser@unsw.edu.au
Ph: + 61 2 9385 4616
Fax: + 61 2 9385 4699

Diploma in Chemistry, University of Göttingen
PhD (Biophysics, Humboldt University, Berlin)
with Prof. Bernd Reif at Leibniz Institute for Molecular Pharmacology, Berlin

Solid-state NMR of proteins, materials, and small molecules.
Collaborations involving groups on campus (e.g. Schools of Chemistry, Material Sciences, BABS) and Sydney University.
Methods development for biological solid-state NMR.

Solid-state NMR of proteins, proton-detection, NMR methods development, intrinsically disordered proteins, membrane proteins, protein structure determination

R. Linser, “Side-chain to backbone correlations from solid-state NMR of perdeuterated proteins through combined excitation and long-range magnetization transfers.”, accepted in J. Biomol. NMR (2011).

R. Linser, M. Dasari, U. Fink, P. Schmieder, J.-M. Lopez del Amo, S. Marcovic, M. Hiller, H. Oschkinat, D. Oesterheld, B. Reif, “Proton detected solid state NMR of fibrillar and membrane proteins”, Angew. Chem., Int. Ed., 50 (19), 4508–4512;
Cover Picture, Angew. Chem., Int. Ed., 50 (19), 4237 (2011).

R. Linser, B. Bardiaux, V. Higman, U. Fink, B. Reif, “Structure calculation from highly unambiguous amide and methyl 1H-1H distance restraints for a micro-crystalline protein with MAS solid state NMR”, J. Am. Chem. Soc., 133 (15), 5905–5912 (2011).

R. Linser, U. Fink, B. Reif, “Detection of dynamic regions in biological solids enabled by spin-state selective NMR experiments”, J. Am. Chem. Soc. 132 (26), 8891–8893 (2010).

R. Linser, U. Fink, B. Reif, “Proton-Detected Scalar Coupling Based Assignment Strategies in MAS Solid-State NMR Spectroscopy Applied to Perdeuterated Proteins”, J. Magn. Reson. 193, 89-93 (2008).